Cell Cycle and Apoptosis

BASIC PRINCIPLES OF THE CELL CYCLE

• Quiescent phase (G0)
• Cells stop proliferating
• Duration varies
• Most cells in normal tissue of adults
• First gap phase (G1)
• Prior to initiation to DNA synthesis
• Separate M and S phases
• Cells preparing for DNA duplication
• Cells receptive to growth signal
• DNA synthesis(s)
• Second gap phase (G2)
• After DNA synthesis
• Before mitosis and completion of cell cycle
• Repair errors
• Mitosis (M)

REGULATIONS OF THE CELL CYCLE 

APOPTOSIS (PROGRAMMED CELL DEATH)

CANCER AND THE CEL CYCLE