Side Effects of Antipsychotics

The side effects of antipsychotics include :

• Extrapyramidal symptoms 
• Stiffness
• Tremor
• Hypersalivation
• Acute dystonia
• Akathisia
• Tardive dyskinesia 
• Anticholinergic symptoms 
• Blurred vision
• Constipation
• Urinary retention
• Dry mouth
• Confusion
• Agitation
• Seizures
• Antihistaminergic symptoms 
• Sedation
• Alpha-blocking effects
• Orthostatic hypotension
• Leucopenia 
• Increased prolactin secretion 
• Amenorrhoea
• Galactorrhoea
• Sexual dysfunction
• Weight gain
• Obstructive jaundice 
• Retinitis pigmentosa (with thioridazine >600 mg/d), 
• Allergic dermatitis / photosensitivity
• Neuroleptic malignant syndrome

Fig 1: Tardive dyskinesia

Akathisia

Acute Dystonia

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