Renal Disease and Pregnancy

Pregnancy in patients with significant renal impairment is associated with increased maternal and fetal complications. With this degree of impairment, most will develop hypertension during pregnancy with an associated increase risk of pre-eclampsia (30%), pre-term delivery and potential deterioration in renal function (20%). The maternal renal outlook is often worse in patients with reflux nephropathy and urinary infection should be screened for and treated. Despite this the fetal outcome is usually good with less than 10% fetal loss.