Red cell morphology

Spherocytosis would be associated with auto immune haemolytic anaemia. Schistocytes or red cell fragments would be more in keeping with mechanical red cell destrcution (e.g. thrombotic thrombocytopenia purpura), bite cells occur with oxidative haemolysis (e.g. G6PD deficiency), Burr cells are seen in renal failure and Pappenheimer bodies are seen in thalassasemia.