Pulmonary Function Tests

FEV1 1.1L (60%) FVC 1.3 L (55%) FEV1/FVC ratio = 84% TLC = 65% predicted RV = 58% predicted TLCO = 55% predicted KCO = 105% predicted

The lung function tests show a significant restrictive defect. Only obesity or a fibrosing disease may fit this picture given the normal/high KCO (i.e. after correcting for alveolar volumes). The most likely answer is obesity, as the gas exchange after correcting for the alveolar volume (TLCO) would tend to be low in fibrosing alveolitis. Both COPD and obliterative bronchiolitis show an obstructive picture but with low TLCO whereas asthma will also produce an obstructive pattern but with normal or high TLCO.

FEV1 1.1L (60%)/ FVC 1.3 L (55%)/ FEV1/FVC ratio = 84%/ TLC = 66% predicted/ RV = 57% predicted/ TLCO = 55% predicted/ KCO = 110% predicted

Acute sickle crisis, systemic lupus erythematosus (SLE) pneumonitis, Scoliosis, Asthma, Cystic fibrosis.

The lung function tests show a significant restrictive defect. Only kyphoscoliosis or a pneumonitis may fit this picture but given the normal/high KCO (i.e. after correcting for alveolar volumes), the most likely answer is kyphoscoliosis as the gas exchange after correcting for the alveolar volume would in fact be high.