Bronchodilators increase the FEV1 and forced vital capacity (FVC) by 15 to 29% over 60 to 120 minutes.
Beta adrenergic agonists are often used as first-line treatment for acute exacerbations of chronic obstructive pulmonary disease, but have not been shown to be superior to anticholinergic agents and the two classes of agent are often used in combination. Side effects are less frequent and milder with ipratropium bromide than with beta agonists.
Metered dose inhalers are cheaper than nebulisers.
Reference
- Stoller JK. Acute exacerbation of chronic obstructive pulmonary disease. N Engl J Med 2002;346(no13):988-994.
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